glp-1 receptor agonist and dpp-4 inhibitor combination contraindicated GLP-1-RA inhibitors in the management of type 2 diabetes DPP4 Inhibitors vs GLP-1 Agonists

(1) PT-141 synthetic peptide appears to be agonistic to melanocortin receptors, which is similar to the natural hormone alpha-MSH

[] Another 8-week trial involving 52 benign prostatic hyperplasia (BPH) patients demonstrated that combined supplementation of lycopene and FruHis resulted in a more significant reduction in insulin-like growth factor 1 (IGF-1), total prostate-specific antigen (TPSA), symptom score, body mass index (BMI), and waist circumference (WC) compared with either supplement alone, with a notable effect observed specifically for IGF-1

Investigations have noted the overexpression of multiple EGFR mediators in conditions such as asthma and COPD

doi: 10.1186/s12906-018-2191-z 85 DehghaniSAlipoorESalimzadehAYaseriMHosseiniMFeinle-BissetCet al